At AACR 2024 Learn How Pepper Tackles ‘Undruggable’ Targets: ML-Driven Transomics Identifies Four Leading Candidates to Treat HCC

April 5-10, San Diego Pepper Bio is on a mission to decipher the root causes of diseases and identify effective treatments—thereby illuminating the fastest, safest path to drug discovery. COMPASS, our ML-driven platform, is built on the world's first and largest proprietary transomics database, integrating genomic, transcriptomic, proteomic, and phosphoproteomic data. Our approach offers a comprehensive understanding of biological systems based not just on expression but also on the activity…

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Interview with Dr. Martin Gershon, Senior Strategic Advisor at Pepper Bio

Tell us a bit about your background. First, I have to start by saying how appreciative I am because I’ve always had exceptional people supporting me and advising me in my career path. I would say that what I am doing now is an amalgam of all the pieces of the mosaic of my life journey which has been dedicated to improving the healthcare system and advancing the development of…

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Pepper Bio hopes to challenge Eroom’s law with new funding

Whether you are a tech optimist or not, you have to acknowledge that progress rarely follows a straight line. While the world keeps getting better at churning semiconductors, we are still struggling to find new drugs to treat resistant diseases, and the process isn’t getting cheaper. Some hope that AI can help, and it likely will — when it comes to biotech, it is much more than a buzzword.  But Boston-based drug discovery…

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Overcoming EGFRi Resistance Through Transomic Analyses

Pepper Bio is on a mission to put an end to untreatable diseases by enabling more effective drug discovery through the use of transomic analysis. We do this using our COMPASS platform that integrates data across the genomic, transcriptomic, proteomic, and phosphoproteomic biological layers to uncover global, functional and causal understanding of complex biological processes. At the 2023 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics conference, hosted by the American Association…

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The future of biomedical research is animal-free

As a scientist focused on tangible data and results, it’s easy to be sceptical about the impact of legislative acts: the path from Congress to the lab is long and winding. Despite the subtle change and lack of immediate impact on patients, the FDA Modernization Act 2.0 is anything but inconsequential. I think, in truth, that it may be the spark needed to ignite the next era of animal-free drug…

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Breast Cancer By A New Name: Redefining Disease For Better Patient Outcomes

Everyone knows someone with cancer, so this question may be confusing, but: Does anyone have cancer anymore? What I mean is: At first, there was cancer. Now, there is chronic myeloid leukemia and acute lymphocytic leukemia; primary colorectal lymphomas and gastrointestinal stromal tumors; and six subgroups of triple-negative breast cancer. We’ve outgrown the blanket term “cancer,” and it’s making a positive difference in how we treat and overcome disease. In…

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